MORGANTOWN, W.Va., Sept. 8 (UPI) — Chemicals used in the production of non-stick cookware and waterproof fabrics appear more likely to have elevated cholesterol levels, U.S. researchers say.
Stephanie J. Frisbee of West Virginia University School of Medicine in Morgantown and colleagues assessed serum lipid levels in 12,476 children and adolescents — average age 11.1 — included in the C8 Health Project, which resulted from the settlement of a class-action lawsuit regarding perfluorooctanoic acid contamination.
Perfluoroalkyl acids — including perfluorooctanoic acid and perfluorooctanesulfonate — are found in drinking water, dust, food packaging, breast milk, cord blood, microwave popcorn, air and occupational exposure. Perfluoroalkyl acids are used in the manufacture of fluoropolymers, which give non-stick heat resistance to cookware and waterproof fabrics and upholstery.
The children and teens submitted blood samples in 2005 and 2006. Among the participants, perfluorooctanoic acid was found in 29.3 nanograms per milliliter compared to a national survey of 3.9 nanograms per milliliter, but perfluorooctanesulfonate concentrations were similar — 19.1 nanograms per milliliter vs. 19.3 nanograms per milliliter.
After factoring for other variables, higher perfluorooctanoic acid levels were linked to increased total cholesterol and low-density lipoprotein, or “bad” cholesterol, and perfluorooctanesulfonate was associated with increased total cholesterol, LDL cholesterol and HDL or “good” cholesterol.
The findings are published in the Archives of Pediatrics & Adolescent Medicine.
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