Timing a Woman's Biological Clock

ROME, June 28 (UPI) — A blood test at age 20 may help women foresee when they will become menopausal, an Iranian researcher says.

Dr. Fahimeh Ramezani Tehrani of Shahid Beheshti University of Medical Sciences in Tehran says the test measures a hormone produced in the ovaries called anti-Mullerian Hormone.


“We developed a statistical model for estimating the age at menopause from a single measurement of anti-Mullerian Hormone concentration in serum from blood samples,” Tehrani says in a statement.

For example, the researchers estimated a 20-year-old woman with a concentration of serum anti-Mullerian Hormone of 2.8 nanograms per milliliter would become menopausal between ages 35 and 38.

A subgroup of 63 women reaching menopause during the study indicated the average difference between the model-predicted age at menopause and the actual age was only a third of a year. The model’s maximum margin of error was 3 to 4 years.

Tehrani and colleagues periodically tested blood, took histories and physically examined 266 women ages 20-49 already enrolled in the large, ongoing Tehran Lipid and Glucose Study.

The findings were presented in Rome at the annual meeting of the European Society of Human Reproduction and Embryology.

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