Supplement May Lessen Diabetic Nephropathy

BETHESDA, Md., Sept. 23 (UPI) — Chromium picolinate may help in treating kidney disease among people with diabetes, U.S. researchers say.

Researchers at the Medical College of Georgia in Augusta link use of the supplement chromium picolinate in diabetic mice with decreased albuminuria — protein in the urine — which is an indicator of kidney disease.


Lead author Mahmood Mozaffari says the study finds diabetic mice with chromium picolinate added to their diet excreted about half as much albumin as their untreated diabetic counterparts.

At the end of six months, the mice were euthanized and their kidneys compared. Those of untreated diabetic mice had marked inflammation not visible in the kidneys of the diabetic mice who had taken the supplement.

Mozaffari says further studies are necessary, especially since it is not clear whether the effect is linked to chromium picolinate or to picolinic acid.

“This clearly raises an important question for us as to whether our observations are related to the provision of picolinic acid from the chromium picolinate or whether the formulation — chromium picolinate — in and of itself, is mediating the effects,” Mozaffari says in a statement.

Mozaffari presented the study at a conference held by the American Physiological Society in Westminster, Colo.

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