Statins May Lower Risk of Blood Clots

MANSFIELD, Conn., May 18 (UPI) — A U.S. review of studies found people at risk for blood clots may be helped by use of statin — a cholesterol lowering drug, researchers say.

Lead author Vanjul Agarwal of the University of Connecticut said the researchers reviewed 10 studies involving more than 900,000 men and women evaluating the effect of statins in preventing venous thromboembolism — clots formed in the deep veins that pose a serious risk of heart attack and stroke.

The study included all types of venous thromboembolism, with a focus on deep vein thrombosis, most commonly involving clots in the lower legs and pulmonary embolism, clots that form in the primary vessels of the lungs after migrating from other areas of the body.

The researchers found statin use benefited patients with all types of venous thromboembolism, including deep vein thrombosis and pulmonary embolism.

“Statins have been found to have anti-inflammatory properties,” Agarwal says in a statement. “Since thrombus formation involves inflammation, statins may reduce venous thrombus formation and thus, lower the odds of developing pulmonary embolism /deep vein thrombosis.”

The study is scheduled to be presented at the ATS International Conference in New Orleans.

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