BOSTON, April 13 (UPI) — Some anti-convulsant medications used for patients with epilepsy may be linked to an increased risk of suicide, U.S. researchers suggest.
Dr. Elisabetta Patorno of Brigham and Women’s Hospital and Harvard Medical School, both in Boston, and colleagues examined health insurance data and medical records from HealthCore Integrated Research Database from 14 states for patients age 15 and older from July 2001 to December 2006.
Anti-convulsant medications mainly are used for patients with epilepsy, but they are also used for bipolar disorder, mania, neuralgia, migraine and neuropathic pain.
“The analyses including violent death produced similar results. Gabapentin users had increased risk in subgroups of younger and older patients, patients with mood disorders, and patients with epilepsy or seizure when compared with carbamazepine,” the study authors said in a statement.
“This exploratory analysis contributes to the understanding of the complex and little-understood relationship between anti-convulsant medication use and suicide risk.”
The study is published in the Journal of the American Medical Association.
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